How Does Sugar Affect Our Brain?

Table of Contents (click to expand)

Sugar affects the brain by triggering a release of dopamine, the “reward” chemical that makes a sweet treat feel good and keeps us coming back. The popular “sugar rush,” however, is a myth: studies find no real mood boost. If anything, sugar leaves us more tired and less alert within an hour, and a steady high-sugar diet can dull memory over time.

There are so many delicious things to eat these days: ice cream, cake, chocolate, flavored sodas and more. All these wonderful things have one ingredient in common: Sugar.

This simple carbohydrate (glucose, in its simplest form) is also added to our coffee and tea (in the form of sucrose, or table sugar). It is also naturally present in many important foods, such as milk (lactose) and fruits (fructose). Therefore, with this ingredient being so widely prevalent in our food, it’s time to find out how it actually affects our brain.

Woman Eating Cupcake
Credits:Africa Studio/Shutterstock

The Reward System

From the very moment that sugar enters your mouth, it is sensed by the tongue’s taste buds and a message is sent to the brain. This sugar-induced signal stimulates the release of dopamine, which is a neurotransmitter responsible for activating the brain’s reward system. Dopamine essentially makes you feel good, so every time you eat sugar, your brain releases dopamine, basically reminding you that eating sugar will make you happy.

This is the same reward pathway that addictive drugs like nicotine and alcohol hijack, which is why you’ll often hear sugar described as addictive. It’s worth being careful with that word, though. In animal studies, rats fed a lot of sugar do show brain changes that look a little like the ones seen with drugs of abuse, including intense craving and a dialing-down of dopamine sensitivity over time. Even so, the effect is far milder than any real drug, and a genuine sugar “addiction” with true withdrawal has never been firmly established in people. What we can safely say is that the dopamine hit gently nudges you to reach for the next sweet thing.

The Mood-Booster?

You’ve probably heard that sugar also boosts serotonin, the neurotransmitter most famous for keeping us in a good mood. It’s a tidy story: we eat sugar, serotonin goes up, we feel happy. What could be wrong with that?

Sadly, it’s not that simple. When researchers actually put it to the test, the famous “sugar rush” pretty much vanished. A 2019 review that pooled 31 studies and over 1,300 people found no mood boost from sugar at any point after eating it. If anything, people felt more tired and less alert within the first hour. So the cheerful serotonin tale makes intuitive sense, but the evidence for sugar reliably lifting your mood just isn’t there, and what tends to follow instead is a blood sugar crash and exhaustion.

Brain Power

A steady diet high in sugar can also chip away at brain power, and one likely culprit is oxidative stress. When the brain has to process a flood of sugar, it churns out more free radicals (nasty little molecules), and the brain is especially vulnerable to them: it burns a lot of fuel but carries relatively few antioxidant defenses. These free radicals attack the fatty membranes of nerve cells, which can leave neurons less able to signal one another cleanly. Over time, that kind of damage is linked to a poorer ability to remember instructions, process ideas, and keep our moods on an even keel. Who knew that too much ice cream could make us cranky!

Another way that sugar can dull our thinking is through the hormone insulin. When sugar enters the body, the pancreas receives a signal to secrete insulin to deal with the excess. Insulin matters in the brain too: it helps strengthen the connections between nerve cells, letting them communicate better and form stronger memories. The problem comes with chronic overload. Eating large amounts of sugar over months and years can make the body, and the brain, less responsive to insulin, a state called insulin resistance. In the hippocampus, the brain’s memory hub, that blunted insulin signaling has been tied to weaker synaptic connections and poorer memory. In other words, it turns out that loading up on cake before an exam might not be such a great idea.

Mood

After a meal that is heavy on sugar, the sugar level in our blood first spikes, then the body releases a wave of insulin to mop it up, and the level can swing back down. When that dip is steep enough, it’s sometimes called a “sugar crash” (or reactive hypoglycemia), and it’s the part of the sugar story that the evidence actually backs up.

This is where those unpleasant after-effects come from. Rather than the cheery lift the “sugar rush” promises, what people more reliably report is feeling irritable, foggy-headed, low on energy, and generally tired out. So the lasting impression sugar leaves on your mood is less of a high and more of a slump. Yikes!

qc7eb

What’s The Alternative?

Whenever you find yourself reaching for comfort, you don’t have to grab the nearest bar of chocolate or rush to the ice cream shop around the corner. Instead, opt for whole grain foods. They keep you feeling full and release their energy slowly, so you sidestep the sharp spike-and-crash that refined sugar sets off.

Another good way to head off a sugar craving is to eat fruit. Fruit does contain sugar, but it comes bundled with fiber, which slows how quickly that sugar hits your bloodstream and keeps those insulin swings gentler.

Therefore, stay happy and sugar-free by biting into that delicious apple, rather than digging your hand into the candy jar!

References (click to expand)
  1. Sugar and the Brain | Harvard Medical School. Harvard Medical School
  2. Mantantzis K, et al. Sugar rush or sugar crash? A meta-analysis of carbohydrate effects on mood. Neuroscience & Biobehavioral Reviews (2019). PubMed
  3. Barnes JN, Joyner MJ. Sugar highs and lows: the impact of diet on cognitive function. The Journal of Physiology (2012). PMC, NCBI